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Systemic delivery of MicroRNA mimics with polyethylenimine elevates pulmonary microRNA levels, but lacks pulmonary selectivity

Reversing pathologic alterations in vascular microRNA (miRNA) expression represents a potential therapeutic strategy for pulmonary hypertension. While polyethylenimine (PEI) has previously been shown to be an effective vehicle for vascular lung-directed delivery of plasmid DNA, it remains unclear wh...

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Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Schlosser, Kenny, Taha, Mohamad, Deng, Yupu, Stewart, Duncan J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753929/
https://ncbi.nlm.nih.gov/pubmed/29251557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045893217750613
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