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Targeting Radiation-Induced G(2) Checkpoint Activation with the Wee-1 Inhibitor MK-1775 in Glioblastoma Cell Lines
The purpose of this study was to determine the capacity of MK-1775, a potent Wee-1 inhibitor, to abrogate the radiation-induced G(2) checkpoint arrest and modulate radiosensitivity in glioblastoma cell models and normal human astrocytes. The radiation-induced checkpoint response of established gliob...
Kaydedildi:
| Yayımlandı: | Mol Cancer Ther |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5753756/ https://ncbi.nlm.nih.gov/pubmed/21992793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0469 |
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