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Targeting the Unfolded Protein Response in Glioblastoma Cells with the Fusion Protein EGF-SubA
Rapidly growing tumors require efficient means to allow them to adapt to fluctuating microenvironments consisting of hypoxia, nutrient deprivation, and acidosis. The unfolded protein response (UPR) represents a defense mechanism allowing cells to respond to these adverse conditions. The chaperone pr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527517/ https://ncbi.nlm.nih.gov/pubmed/23284962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052265 |
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