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Activation of the Unfolded Protein Response Contributes toward the Antitumor Activity of Vorinostat

Histone deacetylase (HDAC) inhibitors represent an emerging class of anticancer agents progressing through clinical trials. Although their primary target is thought to involve acetylation of core histones, several nonhistone substrates have been identified, including heat shock protein (HSP) 90, whi...

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Detalhes bibliográficos
Main Authors: Kahali, Soumen, Sarcar, Bhaswati, Fang, Bin, Williams, Eli S, Koomen, John M, Tofilon, Philip J, Chinnaiyan, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805886/
https://ncbi.nlm.nih.gov/pubmed/20072656
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