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Activation of the Unfolded Protein Response Contributes toward the Antitumor Activity of Vorinostat

Histone deacetylase (HDAC) inhibitors represent an emerging class of anticancer agents progressing through clinical trials. Although their primary target is thought to involve acetylation of core histones, several nonhistone substrates have been identified, including heat shock protein (HSP) 90, whi...

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Autors principals: Kahali, Soumen, Sarcar, Bhaswati, Fang, Bin, Williams, Eli S, Koomen, John M, Tofilon, Philip J, Chinnaiyan, Prakash
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805886/
https://ncbi.nlm.nih.gov/pubmed/20072656
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