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KNOTTIN: the database of inhibitor cystine knot scaffold after 10 years, toward a systematic structure modeling

Knottins, or inhibitor cystine knots (ICKs), are ultra-stable miniproteins with multiple applications in drug design and medical imaging. These widespread and functionally diverse proteins are characterized by the presence of three interwoven disulfide bridges in their structure, which form a unique...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Postic, Guillaume, Gracy, Jérôme, Périn, Charlotte, Chiche, Laurent, Gelly, Jean-Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753296/
https://ncbi.nlm.nih.gov/pubmed/29136213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1084
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