Knottin cyclization: impact on structure and dynamics

BACKGROUND: Present in various species, the knottins (also referred to as inhibitor cystine knots) constitute a group of extremely stable miniproteins with a plethora of biological activities. Owing to their small size and their high stability, knottins are considered as excellent leads or scaffolds...

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Main Authors: Heitz, Annie, Avrutina, Olga, Le-Nguyen, Dung, Diederichsen, Ulf, Hernandez, Jean-François, Gracy, Jérôme, Kolmar, Harald, Chiche, Laurent
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659701/
https://ncbi.nlm.nih.gov/pubmed/19077275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-8-54
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