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Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots

BACKGROUND: Knottins are small, diverse and stable proteins with important drug design potential. They can be classified in 30 families which cover a wide range of sequences (1621 sequenced), three-dimensional structures (155 solved) and functions (> 10). Inter knottin similarity lies mainly betw...

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Hlavní autoři: Gracy, Jérôme, Chiche, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984590/
https://ncbi.nlm.nih.gov/pubmed/21029427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-535
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