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Characterization of Elements Regulating the Nuclear-to-Cytoplasmic Translocation of ICP0 in Late Herpes Simplex Virus 1 Infection

Infected cell protein 0 (ICP0) of herpes simplex virus 1 (HSV-1) is an immediate early protein containing a RING-type E3 ubiquitin ligase. It targets several host factors for proteasomal degradation and subsequently activates viral expression. ICP0 has a nuclear localization sequence and functions i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Samrat, Subodh Kumar, Ha, Binh L., Zheng, Yi, Gu, Haidong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752942/
https://ncbi.nlm.nih.gov/pubmed/29093084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01673-17
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