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Akt3 inhibits adipogenesis and protects from diet-induced obesity via WNK1/SGK1 signaling
Three Akt isoforms, encoded by 3 separate genes, are expressed in mammals. While the roles of Akt1 and Akt2 in metabolism are well established, it is not yet known whether Akt3 plays a role in metabolic diseases. We now report that Akt3 protects mice from high-fat diet–induced obesity by suppressing...
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| Udgivet i: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752373/ https://ncbi.nlm.nih.gov/pubmed/29202451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95687 |
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