Akt3 Deficiency in Macrophages Promotes Foam Cell Formation and Atherosclerosis in Mice

Akt, a serine-threonine protein kinase, exists as three isoforms. The Akt signaling pathway controls multiple cellular functions in the cardiovascular system, and the atheroprotective endothelial cell dependent role of Akt1 has been recently demonstrated. The role of Akt3 isoform in cardiovascular p...

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Main Authors: Ding, Liang, Biswas, Sudipta, Morton, Richard E., Smith, Jonathan D., Hay, Nissim, Byzova, Tatiana, Febbraio, Maria, Podrez, Eugene
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372639/
https://ncbi.nlm.nih.gov/pubmed/22632897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.04.020
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