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Akt3 Deficiency in Macrophages Promotes Foam Cell Formation and Atherosclerosis in Mice

Akt, a serine-threonine protein kinase, exists as three isoforms. The Akt signaling pathway controls multiple cellular functions in the cardiovascular system, and the atheroprotective endothelial cell dependent role of Akt1 has been recently demonstrated. The role of Akt3 isoform in cardiovascular p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ding, Liang, Biswas, Sudipta, Morton, Richard E., Smith, Jonathan D., Hay, Nissim, Byzova, Tatiana, Febbraio, Maria, Podrez, Eugene
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372639/
https://ncbi.nlm.nih.gov/pubmed/22632897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.04.020
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