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WNK1 activates SGK1 to regulate the epithelial sodium channel
WNK (with no lysine [K]) kinases are serine-threonine protein kinases with an atypical placement of the catalytic lysine. Intronic deletions increase the expression of WNK1 in humans and cause pseudohypoaldosteronism type II, a form of hypertension. WNKs have been linked to ion carriers, but the und...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
National Academy of Sciences
2005
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1177404/ https://ncbi.nlm.nih.gov/pubmed/16006511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504422102 |
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