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Protein kinase WNK3 regulates the neuronal splicing factor Fox-1

We report an action of the protein kinase WNK3 on the neuronal mRNA splicing factor Fox-1. Fox-1 splices mRNAs encoding proteins important in synaptic transmission and membrane excitation. WNK3, implicated in the control of neuronal excitability through actions on ion transport, binds Fox-1 and inhi...

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Detalhes bibliográficos
Main Authors: Lee, A-Young, Chen, Wei, Stippec, Steve, Self, Jon, Yang, Fan, Ding, Xiaojun, Chen, She, Juang, Yu-Chi, Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479510/
https://ncbi.nlm.nih.gov/pubmed/23027929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215406109
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