Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions

The development of a highly effective vaccine remains a key strategic goal to aid the control and eventual eradication of Plasmodium falciparum malaria. In recent years, the reticulocyte-binding protein homolog 5 (RH5) has emerged as the most promising blood-stage P. falciparum candidate antigen to...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Payne, Ruth O., Silk, Sarah E., Elias, Sean C., Miura, Kazutoyo, Diouf, Ababacar, Galaway, Francis, de Graaf, Hans, Brendish, Nathan J., Poulton, Ian D., Griffiths, Oliver J., Edwards, Nick J., Jin, Jing, Labbé, Geneviève M., Alanine, Daniel G.W., Siani, Loredana, Di Marco, Stefania, Roberts, Rachel, Green, Nicky, Berrie, Eleanor, Ishizuka, Andrew S., Nielsen, Carolyn M., Bardelli, Martino, Partey, Frederica D., Ofori, Michael F., Barfod, Lea, Wambua, Juliana, Murungi, Linda M., Osier, Faith H., Biswas, Sumi, McCarthy, James S., Minassian, Angela M., Ashfield, Rebecca, Viebig, Nicola K., Nugent, Fay L., Douglas, Alexander D., Vekemans, Johan, Wright, Gavin J., Faust, Saul N., Hill, Adrian V.S., Long, Carole A., Lawrie, Alison M., Draper, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752323/
https://ncbi.nlm.nih.gov/pubmed/29093263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96381
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