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Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

No vaccine has yet proven effective against the blood-stages of Plasmodium falciparum, which cause the symptoms and severe manifestations of malaria. We recently found that PfRH5, a P. falciparum-specific protein expressed in merozoites, is efficiently targeted by broadly-neutralizing, vaccine-induc...

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Bibliografische gegevens
Hoofdauteurs: Williams, Andrew R., Douglas, Alexander D., Miura, Kazutoyo, Illingworth, Joseph J., Choudhary, Prateek, Murungi, Linda M., Furze, Julie M., Diouf, Ababacar, Miotto, Olivo, Crosnier, Cécile, Wright, Gavin J., Kwiatkowski, Dominic P., Fairhurst, Rick M., Long, Carole A., Draper, Simon J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493472/
https://ncbi.nlm.nih.gov/pubmed/23144611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002991
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