A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

The lack of an effective licensed vaccine remains one of the most significant gaps in the portfolio of tools being developed to eliminate Plasmodium falciparum malaria. Vaccines targeting erythrocyte invasion – an essential step for both parasite development and malaria pathogenesis – have faced the...

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Autori principali: Bustamante, Leyla Y., Bartholdson, S. Josefin, Crosnier, Cecile, Campos, Marta G., Wanaguru, Madushi, Nguon, Chea, Kwiatkowski, Dominic P., Wright, Gavin J., Rayner, Julian C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538003/
https://ncbi.nlm.nih.gov/pubmed/23146673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.10.106
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