TR47, A PAR1-BASED PEPTIDE, INHIBITS MELANOMA CELL MIGRATION IN VITRO AND METASTASIS IN VIVO

Activated Protein C (APC) is a serine-protease that displays antithrombotic and anti-inflammatory properties. In addition, cleavage of protease-activated receptor 1 (PAR1) by APC exerts endothelial cytoprotective actions. The effects of APC on endothelial cells may be reproduced by TR47, a PAR1-base...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: de Oliveira, Andreia S., de Almeida, Vitor H., Gomes, Fausto G., Rezaie, Alireza R., Monteiro, Robson Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752140/
https://ncbi.nlm.nih.gov/pubmed/29196264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.11.174
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