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TR47, A PAR1-BASED PEPTIDE, INHIBITS MELANOMA CELL MIGRATION IN VITRO AND METASTASIS IN VIVO
Activated Protein C (APC) is a serine-protease that displays antithrombotic and anti-inflammatory properties. In addition, cleavage of protease-activated receptor 1 (PAR1) by APC exerts endothelial cytoprotective actions. The effects of APC on endothelial cells may be reproduced by TR47, a PAR1-base...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752140/ https://ncbi.nlm.nih.gov/pubmed/29196264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.11.174 |
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