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PAR-1 and Thrombin: The Ties that Bind the Microenvironment to Melanoma Metastasis

Progression of melanoma is dependent on cross-talk between tumor cells and the adjacent microenvironment. The thrombin receptor, Protease Activated Receptor-1 (PAR-1) plays a key role in exerting this function during melanoma progression. PAR-1 and its activating factors, which are expressed on tumo...

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Detalhes bibliográficos
Main Authors: Zigler, Maya, Kamiya, Takafumi, Brantley, Emily C., Villares, Gabriel J., Bar-Eli, Menashe
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206157/
https://ncbi.nlm.nih.gov/pubmed/22009534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1432
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