Beta-catenin inhibits melanocyte migration but induces melanoma metastasis

The canonical Wnt signalling pathway induces the β-catenin/LEF transcription factors. It is activated in various cancers, most characteristically carcinomas, in which it promotes metastatic spread by increasing migration and/or invasion. The Wnt/β-catenin signalling pathway is frequently activated i...

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Bibliographic Details
Main Authors: Gallagher, Stuart J., Rambow, Florian, Kumasaka, Mayuko, Champeval, Delphine, Bellacosa, Alfonso, Delmas, Véronique, Larue, Lionel
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637425/
https://ncbi.nlm.nih.gov/pubmed/22665063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.229
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