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Beta-catenin inhibits melanocyte migration but induces melanoma metastasis
The canonical Wnt signalling pathway induces the β-catenin/LEF transcription factors. It is activated in various cancers, most characteristically carcinomas, in which it promotes metastatic spread by increasing migration and/or invasion. The Wnt/β-catenin signalling pathway is frequently activated i...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637425/ https://ncbi.nlm.nih.gov/pubmed/22665063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.229 |
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