Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation

Metastatic melanoma is hallmarked by elevated glycolytic flux and alterations in cholesterol homeostasis. The contribution of cholesterol transporting receptors for the maintenance of a migratory and invasive phenotype is not well defined. Here, the scavenger receptor class B type I (SCARB1/SR-BI),...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Kinslechner, Katharina, Schörghofer, David, Schütz, Birgit, Vallianou, Maria, Wingelhofer, Bettina, Mikulits, Wolfgang, Röhrl, Clemens, Hengstschläger, Markus, Moriggl, Richard, Stangl, Herbert, Mikula, Mario
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751895/
https://ncbi.nlm.nih.gov/pubmed/28974560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0292
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