Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation

Metastatic melanoma is hallmarked by elevated glycolytic flux and alterations in cholesterol homeostasis. The contribution of cholesterol transporting receptors for the maintenance of a migratory and invasive phenotype is not well defined. Here, the scavenger receptor class B type I (SCARB1/SR-BI),...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Kinslechner, Katharina, Schörghofer, David, Schütz, Birgit, Vallianou, Maria, Wingelhofer, Bettina, Mikulits, Wolfgang, Röhrl, Clemens, Hengstschläger, Markus, Moriggl, Richard, Stangl, Herbert, Mikula, Mario
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751895/
https://ncbi.nlm.nih.gov/pubmed/28974560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0292
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