Malignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation

Metastatic melanoma is hallmarked by elevated glycolytic flux and alterations in cholesterol homeostasis. The contribution of cholesterol transporting receptors for the maintenance of a migratory and invasive phenotype is not well defined. Here, the scavenger receptor class B type I (SCARB1/SR-BI),...

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Bibliografske podrobnosti
izdano v:Mol Cancer Res
Main Authors: Kinslechner, Katharina, Schörghofer, David, Schütz, Birgit, Vallianou, Maria, Wingelhofer, Bettina, Mikulits, Wolfgang, Röhrl, Clemens, Hengstschläger, Markus, Moriggl, Richard, Stangl, Herbert, Mikula, Mario
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751895/
https://ncbi.nlm.nih.gov/pubmed/28974560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0292
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