Loading...
Structural Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40
The mechanistic target of rapamycin complex 1 (mTORC1) controls cell growth and metabolism in response to nutrients, energy levels and growth factors. It contains the atypical kinase mTOR and the RAPTOR subunit that binds to the TOS motif of substrates and regulators. mTORC1 is activated by the smal...
Na minha lista:
| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5750076/ https://ncbi.nlm.nih.gov/pubmed/29236692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25023 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|