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Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1
Mechanistic target of rapamycin complex 1 (mTORC1), necessary for cellular growth, is regulated by intracellular signaling mediating inhibition of mTORC1 activation. Among mTORC1 regulatory binding partners, the role of Proline Rich AKT Substrate of 40 kDa (PRAS40) in controlling mTORC1 activity and...
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| Hoofdauteurs: | , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732982/ https://ncbi.nlm.nih.gov/pubmed/23842089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301455110 |
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