PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity

Diabetes is a multi-organ disease and diabetic cardiomyopathy can result in heart failure, which is a leading cause of morbidity and mortality in diabetic patients. In the liver, insulin resistance contributes to hyperglycaemia and hyperlipidaemia, which further worsens the metabolic profile. Defect...

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Autori principali: Völkers, Mirko, Doroudgar, Shirin, Nguyen, Nathalie, Konstandin, Mathias H, Quijada, Pearl, Din, Shabana, Ornelas, Luis, Thuerauf, Donna J, Gude, Natalie, Friedrich, Kilian, Herzig, Stephan, Glembotski, Christopher C, Sussman, Mark A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell 2014
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936489/
https://ncbi.nlm.nih.gov/pubmed/24408966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201303183
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