Rheb1 is Required for mTORC1 and Myelination in Postnatal Brain Development

mTor kinase is involved in cell growth, proliferation, and differentiation. The roles of mTor activators, Rheb1 and Rheb2, have not been established in vivo. Here, we report that Rheb1, but not Rheb2, is critical for embryonic survival and mTORC1 signaling. Embryonic deletion of Rheb1 in neural prog...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Zou, Jia, Zhou, Liang, Du, Xiao-Xia, Ji, Yifei, Xu, Jia, Tian, Junlong, Jiang, Wanxiang, Zou, Yi, Yu, Shouyang, Gan, Lingxue, Luo, Maowen, Yang, Qiaona, Cui, Yiyuan, Yang, Wanchun, Xia, Xiaoqiang, Chen, Mina, Zhao, Xia, Shen, Ying, Chen, PO Yu, Worley, Paul F., Xiao, Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056331/
https://ncbi.nlm.nih.gov/pubmed/21238928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.020
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi