FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors

During pancreas organogenesis, Neurog3(HI) endocrine-committing cells are generated from a population of Sox9(+) mitotic progenitors with only a low level of Neurog3 transcriptional activity (Neurog3(TA.LO)). Low-level Neurog3 protein, in Neurog3(TA.LO) cells, is required to maintain their mitotic e...

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Bibliografische gegevens
Gepubliceerd in:Genesis
Hoofdauteurs: Bechard, Matthew E., Bankaitis, Eric D., Ustione, Alessandro, Piston, David W., Magnuson, Mark A., Wright, Christopher V.E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750046/
https://ncbi.nlm.nih.gov/pubmed/28772022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23050
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