Chargement en cours...
ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche
During mouse pancreas organogenesis, endocrine cells are born from progenitors residing in an epithelial plexus niche. After a period in a lineage-primed Neurog3(LO) state, progenitors become endocrine committed via upregulation of Neurog3. We find that the Neurog3(LO) to Neurog3(HI) transition is a...
Enregistré dans:
| Publié dans: | Development |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176929/ https://ncbi.nlm.nih.gov/pubmed/30126902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.162115 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|