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Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors

During pancreatic development, proliferating pancreatic progenitors activate the proendocrine transcription factor neurogenin 3 (NEUROG3), exit the cell cycle, and differentiate into islet cells. The mechanisms that direct robust NEUROG3 expression within a subset of progenitor cells control the siz...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Krentz, Nicole A.J., van Hoof, Dennis, Li, Zhongmei, Watanabe, Akie, Tang, Mei, Nian, Cuilan, German, Michael S., Lynn, Francis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517315/
https://ncbi.nlm.nih.gov/pubmed/28441528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.02.006
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