Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells

Synovial sarcoma (SS) is an aggressive soft-tissue sarcoma that is often discovered during adolescence and young adulthood. Despite the name, synovial sarcoma does not typically arise from a synoviocyte but instead arises in close proximity to bones. Previous work demonstrated that mice expressing t...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Barrott, Jared J., Illum, Benjamin E., Jin, Huifeng, Hedberg, Matthew L., Wang, Yanliang, Grossmann, Allie, Haldar, Malay, Capecchi, Mario R., Jones, Kevin B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749548/
https://ncbi.nlm.nih.gov/pubmed/29202462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94955
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