β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition

β-catenin is a master regulator in the cellular biology of development and neoplasia. Its dysregulation is implicated as a driver of colorectal carcinogenesis and the epithelial-mesenchymal transition in other cancers. Nuclear β-catenin staining is a poor prognostic sign in synovial sarcoma, the mos...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Barrott, Jared J., Illum, Benjamin E., Jin, Huifeng, Zhu, Ju-Fen, Mosbruger, Tim, Monument, Michael J., Smith-Fry, Kyllie, Cable, Matthew G., Wang, Yanliang, Grossmann, Allie H., Capecchi, Mario R., Jones, Kevin B.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673197/
https://ncbi.nlm.nih.gov/pubmed/26259251
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