The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis

Synovial sarcomas are aggressive soft-tissue malignancies that express chromosomal translocation-generated fusion genes, SS18-SSX1 or SS18-SSX2 in most cases. Here, we report a mouse sarcoma model expressing SS18-SSX1, complementing our prior model expressing SS18-SSX2. Exome sequencing identified n...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Jones, Kevin B., Barrott, Jared J., Xie, Mingchao, Haldar, Malay, Jin, Huifeng, Zhu, Ju-Fen, Monument, Michael J., Mosbruger, Tim L., Langer, Ellen M., Randall, R. Lor, Wilson, Richard K., Cairns, Bradley R., Ding, Li, Capecchi, Mario R.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014712/
https://ncbi.nlm.nih.gov/pubmed/26947017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.38
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki