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Rare mutations provide unique insight into oncogenic potential of STAT transcription factors
The inappropriate activation of transcription factors, including STATs, is known to promote tumor initiation and progression. The most common mechanisms of misregulation lead to constitutive activation of WT STATs. However, the recent discovery of rare STAT mutations in hematopoietic malignancies su...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749538/ https://ncbi.nlm.nih.gov/pubmed/29199995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98619 |
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