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Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors

Misregulation of transcription factors, including signal transducer and activator of transcription (STAT) proteins, leads to inappropriate gene expression patterns that can promote tumor initiation and progression. Under physiologic conditions, STAT signaling is stimulus-dependent and tightly regula...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Heppler, Lisa N., Frank, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727919/
https://ncbi.nlm.nih.gov/pubmed/29198438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.10.004
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