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ESCO1/2's roles in chromosome structure and interphase chromatin organization

ESCO1/2 acetyltransferases mediating SMC3 acetylation and sister chromatid cohesion (SCC) are differentially required for genome integrity and development. Here we established chicken DT40 cell lines with mutations in ESCO1/2, SMC3 acetylation, and the cohesin remover WAPL. Both ESCO1 and ESCO2 prom...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Kawasumi, Ryotaro, Abe, Takuya, Arakawa, Hiroshi, Garre, Massimiliano, Hirota, Kouji, Branzei, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749162/
https://ncbi.nlm.nih.gov/pubmed/29196537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.306084.117
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