ESCO1/2's roles in chromosome structure and interphase chromatin organization

ESCO1/2 acetyltransferases mediating SMC3 acetylation and sister chromatid cohesion (SCC) are differentially required for genome integrity and development. Here we established chicken DT40 cell lines with mutations in ESCO1/2, SMC3 acetylation, and the cohesin remover WAPL. Both ESCO1 and ESCO2 prom...

Full description

Saved in:
Bibliographic Details
Published in:Genes Dev
Main Authors: Kawasumi, Ryotaro, Abe, Takuya, Arakawa, Hiroshi, Garre, Massimiliano, Hirota, Kouji, Branzei, Dana
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749162/
https://ncbi.nlm.nih.gov/pubmed/29196537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.306084.117
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items