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Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion
Replication fork-associated factors promote genome integrity and protect against cancer. Mutations in the DDX11 helicase and the ESCO2 acetyltransferase also cause related developmental disorders classified as cohesinopathies. Here we generated vertebrate model cell lines of these disorders and cohe...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5356530/ https://ncbi.nlm.nih.gov/pubmed/27636994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11982 |
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