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STAT4 and T-bet control follicular helper T cell development in viral infections
Follicular helper T (Tfh) cells promote germinal center (GC) B cell survival and proliferation and guide their differentiation and immunoglobulin isotype switching by delivering contact-dependent and soluble factors, including IL-21, IL-4, IL-9, and IFN-γ. IL-21 and IFN-γ are coexpressed by Tfh cell...
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| Veröffentlicht in: | J Exp Med |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5748849/ https://ncbi.nlm.nih.gov/pubmed/29212666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170457 |
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