STAT4 and T-bet control follicular helper T cell development in viral infections

Follicular helper T (Tfh) cells promote germinal center (GC) B cell survival and proliferation and guide their differentiation and immunoglobulin isotype switching by delivering contact-dependent and soluble factors, including IL-21, IL-4, IL-9, and IFN-γ. IL-21 and IFN-γ are coexpressed by Tfh cell...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Weinstein, Jason S., Laidlaw, Brian J., Lu, Yisi, Wang, Jessica K., Schulz, Vincent P., Li, Ningcheng, Herman, Edward I., Kaech, Susan M., Gallagher, Patrick G., Craft, Joe
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748849/
https://ncbi.nlm.nih.gov/pubmed/29212666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170457
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