The Transcription Factor STAT3 and Type I Interferons Are Mutually Repressive Insulators for Differentiation of Follicular Helper and T Helper_1 Cells

Follicular helper T (Tfh) cells are required for the establishment of T-dependent B cell memory and high affinity antibody-secreting cells. We have revealed herein opposing roles for signal transducer and activator of transcription 3 (STAT3) and type I interferon (IFN) signaling in the differentiati...

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Autores principales: Ray, John P., Marshall, Heather D., Laidlaw, Brian J., Staron, Matthew M., Kaech, Susan M., Craft, Joe
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992517/
https://ncbi.nlm.nih.gov/pubmed/24631156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.02.005
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