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Dysregulation of Neurotrophin Signaling in the Pathogenesis of Alzheimer Disease and of Alzheimer Disease in Down Syndrome

Neurotrophic factors, including the members of the neurotrophin family, play important roles in the development and maintenance of the nervous system. Trophic factor signals must be transmitted over long distances from axons and dendrites to the cell bodies of neurons. A mode of signaling well suite...

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Библиографические подробности
Опубликовано в: :Free Radic Biol Med
Главные авторы: Chen, Xu-Qiao, Sawa, Mariko, Mobley, William C
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748266/
https://ncbi.nlm.nih.gov/pubmed/29031834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.10.341
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