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Dysregulation of Neurotrophin Signaling in the Pathogenesis of Alzheimer Disease and of Alzheimer Disease in Down Syndrome

Neurotrophic factors, including the members of the neurotrophin family, play important roles in the development and maintenance of the nervous system. Trophic factor signals must be transmitted over long distances from axons and dendrites to the cell bodies of neurons. A mode of signaling well suite...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Chen, Xu-Qiao, Sawa, Mariko, Mobley, William C
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748266/
https://ncbi.nlm.nih.gov/pubmed/29031834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.10.341
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