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LB-100, a novel Protein Phosphatase 2A (PP2A) Inhibitor, Sensitizes Malignant Meningioma Cells to the Therapeutic Effects of Radiation

Atypical and anaplastic meningiomas (AAM) represent 20% of all meningiomas. They are associated with poor outcomes due to their tendency to recur. While surgery and radiation (RT) are first line therapy, no effective systemic medical treatment has been identified. Protein phosphatase 2A (PP2A) is a...

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Détails bibliographiques
Publié dans:Cancer Lett
Auteurs principaux: Ho, Winson SC., Sizdahkhani, Saman, Hao, Shuyu, Song, Hua, Seldomridge, Ashlee, Tandle, Anita, Maric, Dragan, Kramp, Tamalee, Lu, Rongze, Heiss, John D., Camphausen, Kevin, Gilbert, Mark R., Zhuang, Zhengping, Park, Deric M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748254/
https://ncbi.nlm.nih.gov/pubmed/29199006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.11.035
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