LB-100, a novel Protein Phosphatase 2A (PP2A) Inhibitor, Sensitizes Malignant Meningioma Cells to the Therapeutic Effects of Radiation

Atypical and anaplastic meningiomas (AAM) represent 20% of all meningiomas. They are associated with poor outcomes due to their tendency to recur. While surgery and radiation (RT) are first line therapy, no effective systemic medical treatment has been identified. Protein phosphatase 2A (PP2A) is a...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Ho, Winson SC., Sizdahkhani, Saman, Hao, Shuyu, Song, Hua, Seldomridge, Ashlee, Tandle, Anita, Maric, Dragan, Kramp, Tamalee, Lu, Rongze, Heiss, John D., Camphausen, Kevin, Gilbert, Mark R., Zhuang, Zhengping, Park, Deric M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748254/
https://ncbi.nlm.nih.gov/pubmed/29199006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.11.035
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