Istradefylline reduces memory deficits in aging mice with amyloid pathology

Adenosine A(2A) receptors are putative therapeutic targets for neurological disorders. The adenosine A(2A) receptor antagonist istradefylline is approved in Japan for Parkinson’s disease and is being tested in clinical trials for this condition elsewhere. A(2A) receptors on neurons and astrocytes ma...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Orr, Anna G., Lo, Iris, Schumacher, Heike, Ho, Kaitlyn, Gill, Michael, Guo, Weikun, Kim, Daniel H., Knox, Anthony, Saito, Takashi, Saido, Takaomi C., Simms, Jeffrey, Toddes, Carlee, Wang, Xin, Yu, Gui-Qiu, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747997/
https://ncbi.nlm.nih.gov/pubmed/29100987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.10.014
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