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Interrogation of the Atherosclerosis-associated SORT1 Locus with Primary Human Hepatocytes, iPSC-hepatocytes, and Locus-humanized Mice
OBJECTIVE: The noncoding single nucleotide polymorphism rs12740374 has been hypothesized to be the causal variant responsible for liver-specific modulation of SORT1 expression (i.e., expression quantitative trait locus, or eQTL) and, by extension, the association of the SORT1 locus on human chromoso...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746470/ https://ncbi.nlm.nih.gov/pubmed/29097363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310103 |
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