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CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo—Brief Report
OBJECTIVE: Although early proof-of-concept studies of somatic in vivo genome editing of the mouse ortholog of proprotein convertase subtilisin/kexin type 9 (Pcsk9) in mice have established its therapeutic potential for the prevention of cardiovascular disease, the unique nature of genome-editing tec...
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| Udgivet i: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850082/ https://ncbi.nlm.nih.gov/pubmed/26941020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307227 |
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