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FOXO3 induces ubiquitylation of AKT through MUL1 regulation

AKT (also known as protein kinase B, PKB) plays an important role in cell survival or tumor progression. For these reasons, AKT is an emerging target for cancer therapeutics. Previously our studies showed that mitochondrial E3 ubiquitin protein ligase 1 (MUL1, also known as MULAN/GIDE/MAPL) is suppr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Sun-Yong, Kim, Hyo Jeong, Byeon, Hyung Kwon, Kim, Dae Ho, Kim, Chul-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746397/
https://ncbi.nlm.nih.gov/pubmed/29299162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22793
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