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FOXO3 induces ubiquitylation of AKT through MUL1 regulation
AKT (also known as protein kinase B, PKB) plays an important role in cell survival or tumor progression. For these reasons, AKT is an emerging target for cancer therapeutics. Previously our studies showed that mitochondrial E3 ubiquitin protein ligase 1 (MUL1, also known as MULAN/GIDE/MAPL) is suppr...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746397/ https://ncbi.nlm.nih.gov/pubmed/29299162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22793 |
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